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In this work, we emulated a target clinical trial comparing rate of acute healthcare utilization, all-cause mortality, composite cardiovascular events, and kidney disease progression in patients with moderate to advanced CKD initiating GLP1-RAs versus DPP4is in real world practice within the Veterans Healthcare Administration (VHA)

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Cell viability assay For cell viability assay, cells were planted in 96-well plates (34 10 3 per well) after indicated treatment, then incubated with 10% CCK-8 reagent at 37 C for 2 h

Access can also depend on local referral arrangements, service capacity and commissioning decisions